What if We Found Cancer Early Enough to Make a Difference
The Galleri® multi-cancer early detection test detects a cancer signal across more than 50 types of cancer.1,2 It’s now available to eligible Illumina employees and their dependents. To learn more about this benefit, please watch our recorded webinar. View now.
Individuals must meet the clinical eligibility criteria determined by Genome Medical to receive the test.

Finding Cancer Early is Important
Thinking about the possibility of having cancer can be overwhelming, but taking steps to find cancer early can help you feel more in control. Often, the earlier that cancer can be found, the higher the chance of better outcomes.3 70% of cancer deaths in people ages 50-79 are caused by cancers not commonly screened for.4,5,6 In fact, when cancers are diagnosed early before they have had a chance to spread, the overall 5-year survival rate is 4x higher than when diagnosed in later stages.3,7
Galleri Multi-Cancer Early Detection Test
The Galleri test, GRAIL’s multi-cancer early detection test, detects a cancer signal across more than 50 types of cancer, many of which are not commonly screened for today. All that’s required is a simple blood draw.1,2,8
Eligible Illumina employees have access to the Galleri test as an annual benefit, which includes clinical eligibility confirmation and test review by a Genome Medical physician. Annual eligibility is based on a rolling calendar year from when your test results were completed and reported to you.
Benefit Requirements & Eligibility
This employee benefit through Illumina and Genome Medical provides eligible employees access to the Galleri multi-cancer early detection test as an annual benefit. Annual eligibility is based on a rolling calendar year from when your test results were completed and reported to you. If you received Galleri test results in the past, Genome Medical will notify you once you’re eligible to request the test again. Genome Medical’s team of oncology experts has reviewed risk factors that increase a person’s chance to develop cancer to determine who would benefit from the Galleri test. The current criteria are not meant to represent a comprehensive list of all cancer risk factors but are a starting point to offer the Galleri test.
Between the Ages of 22-49
Certain risk factors may put you at an elevated risk for developing cancer. The Galleri test may be right for you if you meet one or more of the following criteria:
- You have a history of cancer (excluding basal or squamous cell carcinomas of the skin) and are more than three years out of treatment. A consultation with a genetic counselor is required if you have had a personal history of cancer and are more than three years out of treatment.
- You have a first degree relative (parent, child and/or full sibling) who has had cancer.
- You are a smoker or have quit smoking in the last 10 years.
- You had previous genetic testing and were found to have a gene mutation confirming an increased cancer risk due to a hereditary cancer syndrome (e.g., BRCA1/2, Lynch syndrome, CHEK2). Please note that a clinical report from an accredited laboratory that performs clinical grade genetic testing is required; this excludes tests from 23andMe, Ancestry.com and other direct to consumer genetic testing companies. A consultation with a genetic counselor is required if you have had a previous gene mutation in order to confirm the finding.

50 or Older
The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those aged 50 or older. The risk of cancer increases as we age, so individuals 50 or older are eligible for the Galleri Test.

Not Eligible At This Time
Currently, the following individuals are not eligible for the Galleri test:
- You have been diagnosed or treated for cancer within the past three years
- This excludes basal or squamous cell carcinomas of the skin
- This also excludes hormonal therapy (e.g., Tamoxifen, Arimidex, Aromasin) for breast cancer; you need to be 3 years past surgery, chemotherapy and/or radiotherapy but can still be taking hormonal therapy
- You are currently pregnant
- You are 21 years old or younger
- You live outside of the United States; Genome Medical is not able to order testing for people who reside outside the US

The Benefits of Multi-Cancer Detection
The Galleri test is intended to be used in addition to, and not replace, other cancer screening tests your health care provider recommends. The Galleri test does not detect all cancers nor does it measure your genetic risk of developing cancer in the future. The Galleri test is a screening test and does not detect all cancers. Further testing is needed to diagnose cancer if a signal is detected.
Test Process
Follow the process with just three steps.
Ordering the Galleri test
The Galleri test must be ordered by a health care provider. If you’re ready to request the test, you’ll be asked to answer a few questions and a Genome Medical physician will review your information and determine if the test is right for you.
To learn more about clinical eligibility before requesting the test, please click here.

Get a Blood Draw
If your test has been authorized by your Genome Medical physician, a Galleri collection kit will be mailed directly to you with directions on how to locate a partner laboratory to have your blood drawn. Please do not open the kit. You must take the kit to the lab unopened.
Make sure you have the following in hand for your blood draw:
-
- Your Galleri Collection kit. It will be shipped directly to you.
- Your completed and printed Test Requisition Form. GRAIL will email this to you after your test has been authorized by Genome Medical.
If you are a current patient who has questions about scheduling a blood draw, please find more information here or contact GRAIL Customer Service at 833-694-2553 or customerservice@grail.com.

Receive Your Results
Your results will be available approximately two weeks after your sample arrives at the GRAIL laboratory. At that time, Genome Medical will contact you via email or phone to review your test results and discuss next steps. Additionally, you’ll have the option to schedule a return of results session to further discuss your results. Once you receive your results, it’s important to share your results and clinical action plan with your primary care physician.
The test does not measure your genetic risk of developing cancer in the future. With the Galleri multi-cancer early detection test, annual screening provides the opportunity to detect more cancers early.
False-positive and false-negative test results can occur. The Galleri test has a low false-positive rate of 0.5% (detecting a cancer signal when no cancer is present).1

Breakthrough Test Performance
This means that the Galleri test reported a “Cancer Signal Detected” result in approximately 52 individuals out of 100 who actually had cancer.1
This means that the Galleri test reported a “Cancer Signal Not Detected” result in approximately 99 individuals out of 100 who do not actually have cancer.1
This means that the Galleri test reported a “Cancer Signal Detected” result 1 in every 200 tests run in individuals who did NOT actually have cancer.1
This means when a cancer signal was detected in an individual who actually had cancer, the first Cancer Signal Origin was correctly predicted in 89 of 100 times.1
Frequently Asked Questions
BETWEEN THE AGES OF 22-49?
Certain risk factors may put you at an elevated risk for developing cancer. The Galleri test may be right for you if you meet one or more of the following criteria:
- You have a history of cancer (excluding basal or squamous cell carcinomas of the skin) and are more than three years out of treatment. A consultation with a genetic counselor is required if you have had a personal history of cancer and are more than three years out of treatment.
- You have a first degree relative (parent, child and/or full sibling) who has had cancer.
- You are a smoker or have quit smoking in the last 10 years.
- You had previous genetic testing and were found to have a gene mutation confirming an increased cancer risk due to a hereditary cancer syndrome (e.g., BRCA1/2, Lynch syndrome, CHEK2). Please note that a clinical report from an accredited laboratory that performs clinical grade genetic testing is required; this excludes tests from 23andMe, Ancestry.com and other direct to consumer genetic testing companies. A consultation with a genetic counselor is required if you have had a previous gene mutation in order to confirm the finding.
50 OR OLDER?
The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those aged 50 or older. The risk of cancer increases as we age, so individuals 50 or older are eligible for the Galleri Test.
CURRENTLY, THE FOLLOWING INDIVIDUALS ARE NOT ELIGIBLE FOR THE GALLERI TEST:
- You have been diagnosed or treated for cancer within the past three years
- This excludes basal or squamous cell carcinomas of the skin
- This also excludes hormonal therapy (e.g., Tamoxifen, Arimidex, Aromasin) for breast cancer; you need to be 3 years past surgery, chemotherapy and/or radiotherapy but can still be taking hormonal therapy
- You are 21 years old or younger
- You are currently pregnant
- You live outside of the United States; Genome Medical is not able to order testing for people who reside outside the US
Results should be available to your ordering provider within 10 business days (Mon — Fri, excluding holidays) from the time your sample was received at the GRAIL laboratory. Your sample will arrive at the laboratory 1-2 business days after your blood draw.
At that time, Genome Medical will contact you via email or phone to schedule an optional genetic counseling session to review your test results and discuss the next steps. Once you receive your results, it’s important to share your results and clinical action plan (which will be provided by Genome Medical) with your primary care provider.
Insurance coverage for bloodwork and imaging studies is generally covered by insurers when there is an indication or reason to order them. Since the Galleri test is a new test, it is possible that your insurance may not cover some of the additional tests. Illumina, GRAIL and Genome Medical can provide resources that may help your provider show medical necessity for coverage for additional tests, but coverage cannot be guaranteed.
For employees with insurance coverage through the Blue Shield plan, if any advanced imaging (MRI, CT, PET/CT scan) is recommended, please contact Collective Health at 1-833-743-3223 and make them aware of the imaging test(s) that is being recommended. Collective Health will contact Blue Shield to preemptively approve the imaging test(s) so that Blue Shield does not deny the claim once it is submitted.
In a large-scale clinical study, the Galleri test had 51.5% sensitivity for all cancers and 76.3% sensitivity in cancers that cause two-thirds of cancer deaths in the US (anus, bladder, colon/rectum, esophagus, head and neck, liver/bile duct, lung, lymphoma, ovary, pancreas, plasma cell neoplasm, and stomach).3,5 Sensitivity measures how often the test correctly identifies the cancer signal when cancer is present (also known as the true positive rate).
The Galleri test had a specificity of 99.5% or false-positive rate of 0.5%, meaning in approximately 200 people tested, only 1 person received a false positive result (a false positive is a test result of “Cancer Signal Detected” when cancer is not present).3
Once your test has been authorized by your Genome Medical physician, a Galleri collection kit will be mailed directly to you with directions on how to locate a laboratory to have your blood drawn. You will need to bring the following with you:
- Your Galleri collection kit
Will be shipped directly to you - Your completed and printed Test Requisition Form
GRAIL will email this to you after your test has been authorized by Genome Medical. Must be printed and brought to your blood draw appointment.
All regular US-based Illumina employees and their dependents (spouses/domestic partners and children) in the United States who meet clinical eligibility may access the test at no cost. Clinical eligibility is currently age 50 years or older or those who are between the ages of 18-49 who have an elevated risk of developing cancer. Eligible employees and their dependents (spouse/domestic partner and children) between the ages of 18-49 may be eligible to receive the test at no cost if any of the elevated risk criteria below are met. If you meet these criteria and you’re interested in the Galleri test, a genetic counseling consultation with one of Genome Medical’s genetic counselors is required. During this session, your personal and family history will be reviewed to confirm eligibility and if criteria are met, Genome Medical will order the Galleri test for you.
Identified Gene Mutation: you had previous genetic testing and were found to have a gene mutation confirming an increased cancer risk due to a hereditary cancer syndrome (e.g., BRCA1/2, Lynch syndrome, CHEK2). Please note that a clinical report from an accredited laboratory that performs clinical grade genetic testing is required; this excludes tests from 23andMe, Ancestry.com and other direct to consumer genetic testing companies.
Prior Cancer: you previously had cancer and completed treatment; excludes basal or squamous cell carcinoma of the skin
Direct Biological Family History of Cancer: you have a biological parent, child, and/or a full brother or sister who has had cancer and falls within one of the criteria below:
- the relative was diagnosed under the age of 50
- the relative has had more than one cancer excluding a basal or squamous cell carcinoma of the skin and/or the second cancer is not a recurrence or metastasis of the first cancer
- or the relative passed away from cancer
The Galleri test is currently not available outside of the US.
If you’re over the age of 50 or meet clinical criteria of being at an elevated risk of developing cancer a genetic counseling consultation is NOT required.
However, if you have had previous genetic testing and were found to have a gene mutation confirming an increased cancer risk due to a hereditary cancer syndrome (e.g., BRCA1/2, Lynch syndrome, CHEK2) a consultation with a genetic counselor is required. Please note that a clinical report from an accredited laboratory that performs clinical grade genetic testing is required; this excludes tests from 23andMe, Ancestry.com and other direct to consumer genetic testing companies.
During your post-test consultation you will meet with a Genome Medical board-certified genetic counselor via video or phone. Your genetic counselor will:
- Review your Galleri test results.
- Provide a clear understanding of what your results mean for you. The Galleri test does not measure your genetic risk of developing cancer in the future. The Galleri test looks for DNA changes in the blood that may be associated with cancer at the time of your blood draw.
- Develop a clinical action plan for your ongoing care that you can share with your physician.
- Learn about recommended next steps.
Additional Information
The Galleri test is recommended for use in adults with an elevated risk for cancer, such as those aged 50 or older. The Galleri test does not detect all cancers and should be used in addition to routine cancer screening tests recommended by a healthcare provider. Galleri is intended to detect cancer signals and predict where in the body the cancer signal is located. Use of Galleri is not recommended in individuals who are pregnant, 21 years old or younger, or undergoing active cancer treatment.
Results should be interpreted by a healthcare provider in the context of medical history, clinical signs and symptoms. A test result of “No Cancer Signal Detected” does not rule out cancer. A test result of “Cancer Signal Detected” requires confirmatory diagnostic evaluation by medically established procedures (e.g. imaging) to confirm cancer.
If cancer is not confirmed with further testing, it could mean that cancer is not present or testing was insufficient to detect cancer, including due to the cancer being located in a different part of the body. False-positive (a cancer signal detected when cancer is not present) and false-negative (a cancer signal not detected when cancer is present) test results do occur. Rx only.